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Faria Zafar Selected Research

Isochromosomes

1/2020DNA replication machinery prevents Rad52-dependent single-strand annealing that leads to gross chromosomal rearrangements at centromeres.
1/2019Heterochromatin suppresses gross chromosomal rearrangements at centromeres by repressing Tfs1/TFIIS-dependent transcription.
12/2016Rad51 and Rad54 promote noncrossover recombination between centromere repeats on the same chromatid to prevent isochromosome formation.

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Faria Zafar Research Topics

Disease

7Parkinson Disease (Parkinson's Disease)
10/2023 - 11/2017
4Neurodegenerative Diseases (Neurodegenerative Disease)
10/2023 - 01/2018
3Synucleinopathies
10/2023 - 01/2018
3Isochromosomes
01/2020 - 12/2016
1Intellectual Disability (Idiocy)
08/2020
1Anosmia
01/2018
1Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome)
01/2018
1Multiple System Atrophy
01/2018

Drug/Important Bio-Agent (IBA)

7alpha-SynucleinIBA
10/2023 - 01/2018
3Mitochondrial DNA (mtDNA)IBA
10/2023 - 11/2017
2Phosphotransferases (Kinase)IBA
01/2018 - 11/2017
2Leucine (L-Leucine)FDA Link
01/2018 - 11/2017
1Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
08/2020
1DNA-Directed DNA Polymerase (Polymerases, DNA)IBA
01/2020
1Rad52 DNA Repair and Recombination ProteinIBA
01/2020
1MethyltransferasesIBA
01/2019
1Colloids (Colloid)IBA
01/2018
1Proteins (Proteins, Gene)FDA Link
12/2016
1EndonucleasesIBA
12/2016

Therapy/Procedure

2Therapeutics
10/2023 - 01/2023
1Transplantation
02/2023